Using Hubertia ambavilla aqueous extract, an endemic plant from Reunion Island, as a reducer and a stabilizer, gold nanoparticles are greenly synthetized according a patented process. Then a coat of glucose, a sugar overconsume by cancerous cells (Warburg effect), is added to the gold nanoparticles, permitting an efficient and quick internalization in targeted cells.
Gold nanoparticles are inert for both healthy and cancerous cells without further intervention. Nevertheless, under a near-infrared laser (also inert if use alone), gold nanoparticles will undergo photothermal heating, resulting in selective hyperthermic cell death, without heating of the adjacent non-tumoral tissue. This double targeting (of gold nanoparticles on one side and the laser on the other side) will permit a decrease of side effect in comparison with current strategy.