The Nanotheranostics project – NT1 is the first and main program carried by TORSKAL. It relates to the treatment of skin cancers by photothermal therapy. The product is a class 3 medical device, consisting of gold nanoparticles designed by green chemistry which is planned to undergo clinical trials in 2022.
Skin cancer is one of the most common cancers worldwide. By the age of 70, 20% of Americans will be diagnosed of skin cancer leading to a total treatment cost of $8.1 billion per year only in the US. It is characterized by an abnormal growth of skin cells, most often on skin exposed to the sun. Basal cell carcinomas and squamous cell carcinomas are the two main forms of skin cancers and they are usually not lethal as they evolve slowly and almost do not spread. As they occur on sun-exposed skin, surgical treatment of these tumors could lead to visible scars and disfiguration. Melanomas are the third form of skin cancer and the most dangerous as it evolves very quickly and is able to spread to other parts of the body. Hence, it needs to be treated as soon as diagnosed as a matter of one day can change the prognosis. As of now, the 5-years survival rate for an advanced melanoma is below 40%.